NEAR MISS: CLINICAL CASES OF PREGNANCY OUTCOMES IN WOMEN WITH COVID-19

Abstract

COVID-19 leads to cytokine storm, systemic inflammatory response and coagulopathy, which is one of the worst prognostic factors. Coagulopathy in COVID-19 is accompanied by a pronounced increase in the level of D-dimer and degradation products of fibrin / fibrinogen, while deviations of other indicators (prothrombin time, activated partial thromboplastin time, platelet count) are relatively rare at the onset of the disease. All pregnant women are offered a screening test for coagulation, including the determination of the level of D-dimer and fibrinogen. For coagulopathy associated with COVID-19, empiric anticoagulant therapy is required to prevent venous thrombosis and thromboembolism, as well as standard maintenance therapy for sepsis-induced coagulopathy or disseminated intravascular coagulation syndrome.

Keywords

• covid‐19
• беременность
• нарушение свертываемости крови
• коагулопатия
• двс-синдром
• антикоагулянтная терапия
• профилактика