Resistance to ABT-199 induced by microenvironmental signals in chronic lymphocytic leukemia can be counteracted by CD20 antibodies or kinase inhibitors

• Rachel Thijssen,
• Erik Slinger,
• Katinka Weller,
• Christian R. Geest,
• Tim Beaumont,
• Marinus H.J. van Oers,
• Arnon P. Kater,
• Eric Eldering

Affiliations

Rachel Thijssen

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam;Department of Hematology, Academic Medical Center, University of Amsterdam

Erik Slinger

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam;Department of Hematology, Academic Medical Center, University of Amsterdam

Katinka Weller

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam

Christian R. Geest

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam

Tim Beaumont

AIMM Therapeutics, Amsterdam

Marinus H.J. van Oers

Department of Hematology, Academic Medical Center, University of Amsterdam;Lymphoma and Myeloma Center Amsterdam, LYMMCARE, The Netherlands

Arnon P. Kater

Department of Hematology, Academic Medical Center, University of Amsterdam;Lymphoma and Myeloma Center Amsterdam, LYMMCARE, The Netherlands

Eric Eldering

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam;Lymphoma and Myeloma Center Amsterdam, LYMMCARE, The Netherlands