The mitochondrial paradox

Sophie L Penman; Rebecca L Jensen; Robyn T Kiy; Amy E Chadwick

doi:10.7554/eLife.59140

eLife (Jun 2020)

The mitochondrial paradox

Sophie L Penman,
Rebecca L Jensen,
Robyn T Kiy,
Amy E Chadwick

Affiliations

Sophie L Penman: ORCiD; MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, United Kingdom; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
Rebecca L Jensen: ORCiD; MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, United Kingdom; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
Robyn T Kiy: ORCiD; MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, United Kingdom; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
Amy E Chadwick: ORCiD; MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, United Kingdom; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom

DOI: https://doi.org/10.7554/eLife.59140
Journal volume & issue: Vol. 9

Abstract

Read online

A structural motif that is found in two cancer drugs may be responsible for their ability to tackle cancers and for the side-effects caused by the drugs.

Published in eLife

ISSN: 2050-084X (Online)
Publisher: eLife Sciences Publications Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Biology (General)
Website: https://elifesciences.org

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Abstract

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