Let-7i-5p maintains the stemness via R-spondin2/Wnt pathway in hepatocellular carcinoma

• Qinghua Wei,
• Xueshan Dai,
• Jiahui Wei,
• Wenwei Sun,
• Xiaoqian Yang,
• Yi Ding,
• Yuxin Zhang,
• Xin Guo,
• Yi Chen

Affiliations

Qinghua Wei

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China

Xueshan Dai

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China

Jiahui Wei

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Center for Basic Medical Research, TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300457, China

Wenwei Sun

Division of Cell, Developmental and Integrative Biology, School of Medicine, South China University of Technology, Guangzhou, Guangdong 510006, China

Xiaoqian Yang

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China

Yi Ding

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China

Yuxin Zhang

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China

Xin Guo

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China; Corresponding authors. College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China.

Yi Chen

College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Chongqing 400716, China; Pharmacology of Chinese Materia Medica – the Key Discipline Constructed by the State Administration of Traditional Chinese Medicine, Chongqing 400716, China; National Demonstration Center for Experimental Pharmacy Education (Southwest University), Chongqing 400716, China; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Chongqing 400716, China; Corresponding authors. College of Pharmaceutical Sciences & Chinese Medicine, Southwest University, Chongqing 400716, China.