Acta Biomedica Scientifica (May 2012)
ROC-ANALYSIS OF NEUROIMMUNOLOGIC INDICES IN PATIENTS WITH CHRONIC PSYCHOGENIC URTICARIA
Abstract
Psychological stress connects with increased level of substance P, wherewith there may be interconnection between psychosomatic component and neuroimmunologic one in the chronic urticaria. Modern methods of findings statistical manipulation have been used in this work. Neuroimmunologic criteria of psychogenic urticaria were defined by the use of ROC-analysis. Substance P role in the pathogenesis of the disease have been indicated, correlation between substance P level and angiotensin converting enzyme (ACE) activity have been corroborated. Assessment of anxiety disorders level have been carried out.