Communications Biology (Jan 2021)

Algorithms for the selection of fluorescent reporters

  • Prashant Vaidyanathan,
  • Evan Appleton,
  • David Tran,
  • Alexander Vahid,
  • George Church,
  • Douglas Densmore

DOI
https://doi.org/10.1038/s42003-020-01599-5
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 8

Abstract

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Vaidyanathan et al. present a heuristic algorithm for the selection of fluorescent reporters in the context of single-cell analysis. They present a tool to enable biologists to design multi-colour fluorophore panels based on specific equipment’s configurations. The authors demonstrate the efficacy of their algorithm by comparing computational predictions with experimental observations.