Nature Communications (Mar 2022)

Acquiring new memories in neocortex of hippocampal-lesioned mice

  • Wenhan Luo,
  • Di Yun,
  • Yi Hu,
  • Miaomiao Tian,
  • Jiajun Yang,
  • Yifan Xu,
  • Yong Tang,
  • Yang Zhan,
  • Hong Xie,
  • Ji-Song Guan

DOI
https://doi.org/10.1038/s41467-022-29208-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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Hippocampal lesioned mice form new memories. Here, the authors show the lateral entorhinal cortex modulates learning-induced cortical long-range gamma synchrony in a hippocampal-dependent manner and artificially induced cortical gamma synchrony across cortical areas improved memory encoding in hippocampal lesioned mice.