Nature Communications (Apr 2024)
A pair of atypical NLR-encoding genes confers Asian soybean rust resistance in soybean
- Qingnan Hao,
- Hongli Yang,
- Shuilian Chen,
- Chanjuan Zhang,
- Limiao Chen,
- Dong Cao,
- Songli Yuan,
- Wei Guo,
- Zhonglu Yang,
- Yi Huang,
- Yanhui Qu,
- Lucy Qin,
- Xiaoyan Sheng,
- Xueyan Wang,
- Chandrani Mitra,
- Heng Zhong,
- John Dawson,
- Eric Bumann,
- Wenling Wang,
- Yaping Jiang,
- Guozhu Tang,
- Ryan Carlin,
- Haifeng Chen,
- Qingli Liu,
- Zhihui Shan,
- Xinan Zhou
Affiliations
- Qingnan Hao
- Soybean Genetics and breeding team, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Hongli Yang
- Chinese Academy of Agricultural Sciences/Key Laboratory for Biological Sciences of Oil Crops, Ministry of Agriculture and Rural Affairs
- Shuilian Chen
- Soybean Collaborative Innovation Center, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Chanjuan Zhang
- Soybean Genetics and breeding team, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Limiao Chen
- Soybean Genetics and breeding team, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Dong Cao
- Soybean Genetics and breeding team, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Songli Yuan
- Chinese Academy of Agricultural Sciences/Key Laboratory for Biological Sciences of Oil Crops, Ministry of Agriculture and Rural Affairs
- Wei Guo
- Chinese Academy of Agricultural Sciences/Key Laboratory for Biological Sciences of Oil Crops, Ministry of Agriculture and Rural Affairs
- Zhonglu Yang
- Soybean Collaborative Innovation Center, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Yi Huang
- Soybean Collaborative Innovation Center, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Yanhui Qu
- The Graduate School of Chinese Academy of Agricultural Sciences
- Lucy Qin
- Syngenta Crop Protection, LLC, Research Triangle Park
- Xiaoyan Sheng
- Syngenta Crop Protection, LLC, Research Triangle Park
- Xueyan Wang
- Syngenta Crop Protection, LLC, Research Triangle Park
- Chandrani Mitra
- Syngenta Crop Protection, LLC, Research Triangle Park
- Heng Zhong
- Syngenta Crop Protection, LLC, Research Triangle Park
- John Dawson
- Syngenta Crop Protection, LLC, Research Triangle Park
- Eric Bumann
- Syngenta Crop Protection, LLC, Research Triangle Park
- Wenling Wang
- Syngenta Crop Protection, LLC, Research Triangle Park
- Yaping Jiang
- Syngenta Crop Protection, LLC, Research Triangle Park
- Guozhu Tang
- Syngenta Crop Protection, LLC, Research Triangle Park
- Ryan Carlin
- Syngenta Crop Protection, LLC, Research Triangle Park
- Haifeng Chen
- Soybean Collaborative Innovation Center, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- Qingli Liu
- Syngenta Crop Protection, LLC, Research Triangle Park
- Zhihui Shan
- Chinese Academy of Agricultural Sciences/Key Laboratory for Biological Sciences of Oil Crops, Ministry of Agriculture and Rural Affairs
- Xinan Zhou
- Soybean Genetics and breeding team, Institute of Oil Crops Research, Chinese Academy of Agriculture Sciences
- DOI
- https://doi.org/10.1038/s41467-024-47611-y
- Journal volume & issue
-
Vol. 15,
no. 1
pp. 1 – 11
Abstract
Abstract Asian soybean rust (ASR), caused by Phakopsora pachyrhizi, is a devastating disease that is present in all major soybean-producing regions. The limited availability of resistant germplasm has resulted in a scarcity of commercial soybean cultivars that are resistant to the disease. To date, only the Chinese soybean landrace SX6907 has demonstrated an immune response to ASR. In this study, we present the isolation and characterization of Rpp6907-7 and Rpp6907-4, a gene pair that confer broad-spectrum resistance to ASR. Rpp6907-7 and Rpp6907-4 encode atypic nucleotide-binding leucine-rich repeat (NLR) proteins that are found to be required for NLR-mediated immunity. Genetic analysis shows that only Rpp6907-7 confers resistance, while Rpp6907-4 regulates Rpp6907-7 signaling activity by acting as a repressor in the absence of recognized effectors. Our work highlights the potential value of using Rpp6907 in developing resistant soybean cultivars.
