Nature Communications (May 2022)

Polymer-coated carbon nanotube hybrids with functional peptides for gene delivery into plant mitochondria

  • Simon Sau Yin Law,
  • Geoffrey Liou,
  • Yukiko Nagai,
  • Joan Giménez-Dejoz,
  • Ayaka Tateishi,
  • Kousuke Tsuchiya,
  • Yutaka Kodama,
  • Tsuyohiko Fujigaya,
  • Keiji Numata

DOI
https://doi.org/10.1038/s41467-022-30185-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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The delivery of genetic material into plants is challenging due to the cell wall barrier. Here, the authors hybridize polymer-coated carbon nanotubes with functional peptides to deliver plasmid DNA cargo into intact plant mitochondria for transient expression and homologous recombination at high efficiency.