Nutrients (Jun 2024)

Impact of Preoperative Malnutrition on Patients with Pancreatic Neoplasms Post-Duodenopancreatectomy: A Retrospective Cohort Study

  • Alvarez Pellegrinelli,
  • Stefano Mancin,
  • Alberto Brolese,
  • Stefano Marcucci,
  • Ornella Roat,
  • Emanuela Morenghi,
  • Sara Morales Palomares,
  • Daniela Cattani,
  • Diego Lopane,
  • Alessandra Dacomi,
  • Chiara Coldani,
  • Giuseppina Tomaiuolo,
  • Susy Dal Bello,
  • Giovanni Capretti,
  • Beatrice Mazzoleni

DOI
https://doi.org/10.3390/nu16121839
Journal volume & issue
Vol. 16, no. 12
p. 1839

Abstract

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Background: Preoperative malnutrition is a significant factor in patients with pancreatic tumors undergoing pancreaticoduodenectomy. The aim of this study was to assess the association between preoperative malnutrition and delayed discharge within a ten-day timeframe and potential correlations between preoperative malnutrition and postoperative surgical complications. Methods: A retrospective cohort study was conducted, recruiting a final sample of 79 patients with benign or malignant cephalic pancreatic tumors from 2015 to 2022. The risk of malnutrition was assessed using the Malnutrition Universal Screening Tool, while length of hospital stay and relevant clinical data were extracted from clinical documentation. Results: The preoperative malnutrition risk was high in 21.52% of the sample, moderate in 36.71%, and low in 41.77%. Body mass index (BMI) (p = 0.007) and postoperative surgical complications (p p = 0.122), or postoperative surgical complications (p = 0.874). Conclusions: Postoperative complications and BMI emerge as significant risk factors. The limited sample size may have compromised the collection of homogeneous and significant data. Future studies should evaluate the implementation of personalized nutritional screening tools, nutritional assessment plans, and the involvement of specialized health professionals.

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