Long-Term Survival of a Child with Atypical Teratoid-Rhabdoid Tumor and Acute Lymphoblastic Leukemia: A Case Report
Kolcheva Maria Andreevna,
Kumirova Ella Vyacheslavovna,
Gorbatykh Svetlana Valeryevna,
Makhmudova Gunai Nariman,
Livshits Matvey Igorevich,
Chmutin Gennadiy Yegorovich,
Kislyakov Alexey Nikolaevich,
Umerenkov Viktor Nikolaevich,
Manuel de Jesus Encarnacion Ramirez,
Nicola Montemurro
Affiliations
Kolcheva Maria Andreevna
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Kumirova Ella Vyacheslavovna
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Gorbatykh Svetlana Valeryevna
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Makhmudova Gunai Nariman
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Livshits Matvey Igorevich
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Chmutin Gennadiy Yegorovich
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Kislyakov Alexey Nikolaevich
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Umerenkov Viktor Nikolaevich
State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia
Manuel de Jesus Encarnacion Ramirez
Department of Neurosurgery, Peoples’ Friendship University of Russia (RUDN University), 117198 Moscow, Russia
Nicola Montemurro
Department of Neurosurgery, Azienda Ospedaliero Universitaria Pisana, 56100 Pisa, Italy
Atypical teratoid-rhabdoid tumor (AT/RT) is a rare but one of the most aggressive embryonal tumors of the central nervous system (CNS), most often occurring in children under 3 years of age. AT/RT accounts for about 1–2% of all CNS neoplasms and has a very poor prognosis, high risk of secondary tumor development, recurrence and/or metastasis in patients in remission and limited therapeutic potential. The clinical manifestations are usually symptoms of increased intracranial pressure. The mainstay of tumor treatment is complex chemotherapy combined with radiation therapy. A clinical case of sequential occurrence of two cancers (AT/RT and leukemia) in a 3-year-old girl is presented.
