Nature Communications (Sep 2019)

Oligodendrocytes express synaptic proteins that modulate myelin sheath formation

  • Alexandria N. Hughes,
  • Bruce Appel

DOI
https://doi.org/10.1038/s41467-019-12059-y
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Oligodendrocyte processes can detect and respond to axonal vesicular release. The authors here show in zebrafish that transsynaptic adhesion molecules, molecules that promote synapse formation and maturation in neurons, are expressed by oligodendrocytes and required for myelin sheath growth.