Elemental Laser-Plasma Analysis of Pointed Gourd Leaves for Diabetes Management
Tejmani Kumar,
Prashant K. Rai,
Abhishek K. Rai,
Nilesh K. Rai,
Awadhesh K. Rai,
Christian G. Parigger,
Geeta Watal,
Suman Yadav
Affiliations
Tejmani Kumar
Laser Spectroscopy Laboratory, Department of Physics, University of Allahabad, Prayagraj 211 002, India
Prashant K. Rai
Alternative Therapeutics Unit, Drug Development Division, Medicinal Research Laboratory, Department of Chemistry, University of Allahabad, Prayagraj 211 002, India
Abhishek K. Rai
Department of Earth and Planetary Sciences, University of Allahabad, Prayagraj 211 002, India
Nilesh K. Rai
Department of Physics, Chowdhary Mahadev Prasad Degree College, Prayagraj 211 002, India
Awadhesh K. Rai
Laser Spectroscopy Laboratory, Department of Physics, University of Allahabad, Prayagraj 211 002, India
Christian G. Parigger
Physics and Astronomy Department, University of Tennessee, University of Tennessee Space Institute, Center for Laser Applications, 411 B.H. Goethert Parkway, Tullahoma, TN 37388-9700, USA
Geeta Watal
Alternative Therapeutics Unit, Drug Development Division, Medicinal Research Laboratory, Department of Chemistry, University of Allahabad, Prayagraj 211 002, India
Suman Yadav
Department of Chemistry, Swami Shraddhanand College, University of Delhi, Alipur, New Delhi 110 036, India
This interdisciplinary work communicates the identification and quantification of elements responsible for the bioactive potency of leaves from pointed gourd, trichosanthes dioica, using laser-induced breakdown spectroscopy (LIBS). Calibration-free LIBS determines the presence of various trace and major elements, their concentrations, and ratios in which they are present in the leaves. The presence of specific elemental ratios of magnesium/sodium and magnesium/potassium could be promising for managing diabetes mellitus. Variable doses of aqueous extract from trichosanthes dioica leaves are administered for determination of the most effective one. Based on encouraging results, the extract could be harvested to serve as anti-diabetic medication for diabetes and associated symptoms.
