Antibacterial activity of houttuynin sodium bisulphate (HSB)

Abstract

Houttuynin sodium bisulphate (HSB), a-hydroxyl-capryl-ethyl-sodium-sulphonate, is a product formed by reacting sodium bisulphate with houttuynin, which is obtained from a medicinal herb Houttuynia cordata Thunb. The antibacterial activity of HSB was measured by optical density. Minimum inhibitory concentrations at 50% and 90% inhibition level (MIC50 and MIC90) for Escherichia coli varied from 0.5 to 0.6 mg/ml and from 2.6 to 2.7 mg/ml, respectively. For Staphylococcus aureus MIC50 and MIC90 varied from 0.2 to 0.3 mg/ml and from 0.4 to 0.5 mg/ml, respectively. In comparison with MIC of antibiotics currently used for treatment of disorders caused by S. aureus or by E. coli were MICs of HSB relatively high and general antibacterial activity very weak.

Keywords

• houttuynin sodium bisulphate
• houttuynia cordata
• antibacterial activity
• escherichia coli
• staphylococcus aureus