Research Progress on the Correlation of Atopic Dermatitis with Gut Microbiota

Abstract

Qiuyu Mao,1 Xinyi Wang,1 Haibin Cai,1 Jingyi Yang,2 Yiwen Zhang,2 Wei Min,2 Qihong Qian,2 Yibin Zeng1 1Department of Dermatology, Minhang Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Dermatology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, People’s Republic of ChinaCorrespondence: Qihong Qian; Yibin Zeng, Email [email protected]; [email protected]: Atopic dermatitis (AD) is a common skin disease, the pathogenesis of which has not been fully elucidated. The gut microbiota is the largest micro-ecosystem in the human body that affects the immune system and skin barrier function. Recent studies have shown that in addition to the environmental factors, skin barrier, genetic factors and immune response, gut microbiota disturbance may also cause AD. This review described the correlation of AD with gut microbiota and existing research status of AD treatment via targeting gut microbiota.Keywords: atopic dermatitis, gut microbiota, fecal microbiota transplantation

Keywords

• atopic dermatitis
• gut microbiota
• fecal microbiota transplantation