Menopause Review (Feb 2011)

Ocena wskaźnika metabolizmu kostnego oraz wyznaczenie zakresu jego wartości prawidłowych u zdrowych kobiet i mężczyzn

  • Wiesław Tryniszewski,
  • Anna Sobczuk,
  • Magdalena Górska-Chrząstek,
  • Mariusz Gadzicki,
  • Iwona Raciborska,
  • Andrzej Zając,
  • Zbigniew Maziarz

Journal volume & issue
Vol. 15, no. 1
pp. 50 – 57

Abstract

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Introduction: Bone mass and metabolism undergo different changes with age. Osteoporosis is an importantproblem for both men and women. The assessment of bone metabolism includes bone mineral density andquality. Several years of experience with our own method of bone scintigraphy allowed us to determine IBM andits range of normal values in men and women. Aim: To establish IBM and define its range of normal values in healthy men and women. To compare IBMand BMD and their possible use in the skeletal system assessment. Material and methods: 117 healthy women and 90 healthy men underwent the assessment: anthropometric,biochemical, hormonal, vascular and densitometric examinations using the DXA technique. IBM establishingand its normal range of values in men and women. Results: Normal results of anthropometric, biochemical, hormonal, vascular and densitometric examinationsexclude osteoporosis. The range of IBM normal values was comparable in men and women. In men, the minimalvalue of IBM was slightly higher than in women. The study allowed us to determine the normal range of IBMvalues. In men, a wider range of normal IBM values was observed. Conclusions: Our own program and method allowed us to establish a bone metabolism indicator and itsnormal range of values in healthy men and women. It was observed that the speed of bone changes in men andwomen was similar, yet, IBM values in men were slightly higher. IBM along with densitometry completes theskeletal system diagnostics in healthy patients, in osteoporosis and other pathological conditions.

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