Nature Communications (Mar 2019)

Simulations suggest a constrictive force is required for Gram-negative bacterial cell division

  • Lam T. Nguyen,
  • Catherine M. Oikonomou,
  • H. Jane Ding,
  • Mohammed Kaplan,
  • Qing Yao,
  • Yi-Wei Chang,
  • Morgan Beeby,
  • Grant J. Jensen

DOI
https://doi.org/10.1038/s41467-019-09264-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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It is unclear whether a constrictive force is exerted on the membrane from inside during bacterial cell division, or cell wall remodeling alone drives membrane constriction from outside. Here, the authors use simulations to explore different mechanisms for cell wall division, supporting that a constrictive force is required.