Nature Communications (Apr 2020)
Sex chromosome evolution in parasitic nematodes of humans
- Jeremy M. Foster,
- Alexandra Grote,
- John Mattick,
- Alan Tracey,
- Yu-Chih Tsai,
- Matthew Chung,
- James A. Cotton,
- Tyson A. Clark,
- Adam Geber,
- Nancy Holroyd,
- Jonas Korlach,
- Yichao Li,
- Silvia Libro,
- Sara Lustigman,
- Michelle L. Michalski,
- Michael Paulini,
- Matthew B. Rogers,
- Laura Teigen,
- Alan Twaddle,
- Lonnie Welch,
- Matthew Berriman,
- Julie C. Dunning Hotopp,
- Elodie Ghedin
Affiliations
- Jeremy M. Foster
- Division of Protein Expression & Modification, New England Biolabs
- Alexandra Grote
- Department of Biology, Center for Genomics and Systems Biology, New York University
- John Mattick
- Institute for Genome Science, University of Maryland School of Medicine
- Alan Tracey
- Wellcome Sanger Institute
- Yu-Chih Tsai
- Pacific Biosciences
- Matthew Chung
- Institute for Genome Science, University of Maryland School of Medicine
- James A. Cotton
- Wellcome Sanger Institute
- Tyson A. Clark
- Pacific Biosciences
- Adam Geber
- Department of Biology, Center for Genomics and Systems Biology, New York University
- Nancy Holroyd
- Wellcome Sanger Institute
- Jonas Korlach
- Pacific Biosciences
- Yichao Li
- School of Electrical Engineering and Computer Science, Ohio University
- Silvia Libro
- Division of Protein Expression & Modification, New England Biolabs
- Sara Lustigman
- Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center
- Michelle L. Michalski
- Department of Biology and Microbiology, University of Wisconsin Oshkosh
- Michael Paulini
- European Molecular Biology Laboratory, European Bioinformatics Institute
- Matthew B. Rogers
- Department of Surgery, UPMC Children’s Hospital of Pittsburgh
- Laura Teigen
- Department of Biology and Microbiology, University of Wisconsin Oshkosh
- Alan Twaddle
- Department of Biology, Center for Genomics and Systems Biology, New York University
- Lonnie Welch
- School of Electrical Engineering and Computer Science, Ohio University
- Matthew Berriman
- Wellcome Sanger Institute
- Julie C. Dunning Hotopp
- Institute for Genome Science, University of Maryland School of Medicine
- Elodie Ghedin
- Department of Biology, Center for Genomics and Systems Biology, New York University
- DOI
- https://doi.org/10.1038/s41467-020-15654-6
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 12
Abstract
Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome evolution is highly plastic.