Translate to divide: сontrol of the cell cycle by protein synthesis

Abstract

Protein synthesis underpins much of cell growth and, consequently, cell multiplication. Understanding how proliferating cells commit and progress into the cell cycle requires knowing not only which proteins need to be synthesized, but also what determines their rate of synthesis during cell division.

Keywords

• protein synthesis
• ribosome biogenesis
• ribosome profiling
• START
• translational control