Acta Médica Portuguesa (Jul 2022)

Life-Threatening Wunderlich Syndrome Associated with Apixaban and the Complexity of Anticoagulation Management in Bleeding Patients: A Case Report

  • Sérgio Maltês,
  • Cristina Carvalho Gouveia,
  • Filipa Serrazina,
  • Marta Rebelo

DOI
https://doi.org/10.20344/amp.16941
Journal volume & issue
Vol. 36, no. 3
pp. 206 – 209

Abstract

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Wunderlich syndrome is a rare and possibly life-threatening haemorrhagic syndrome presenting as spontaneous nontraumatic renal rupture with subcapsular and perinephric haemorrhage. Apixaban, a direct oral anticoagulant recommended in patients with atrial fibrillation, has previously been associated with atraumatic solid organ rupture but, to date, no case of apixaban-related Wunderlich syndrome has been reported. We report a rare case of Wunderlich syndrome associated with apixaban while addressing the difficulties face by clinicians when managing anticoagulation in bleeding patients.

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