Tomography (Nov 2021)

Cryoablation in Locoregional Management of Complex Unresectable Chest Neoplasms

  • Roberto Iezzi,
  • Andrea Contegiacomo,
  • Alessandro Posa,
  • Nico Attempati,
  • Ernesto Punzi,
  • Alessandro Tanzilli,
  • Stefano Margaritora,
  • Maria Teresa Congedo,
  • Alessandra Cassano,
  • Emilio Bria,
  • Luca Tagliaferri,
  • Vincenzo Valentini,
  • Cesare Colosimo,
  • Riccardo Manfredi

DOI
https://doi.org/10.3390/tomography7040057
Journal volume & issue
Vol. 7, no. 4
pp. 688 – 696

Abstract

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Rationale and Objectives: The aim of our retrospective study was to assess the safety and feasibility of cryoablation in high-risk patients with complex chest neoplastic lesions. Materials and Methods: Twenty patients with complex chest malignancies, both primary and secondary, located in the mediastinum, lung, and chest wall, underwent percutaneous CT-guided cryoablation treatments. Procedural success as well as complications were evaluated. Results: A total of 24 neoplastic lesions were treated (mean diameter: 27 mm; range: 7–54 mm). Technical success was obtained in all patients, without major complications or intraprocedural death. A pneumothorax not requiring a drainage tube placement was registered in 50% of patients, while 3/24 patients had a grade 3 pneumothorax requiring a chest tube placement. Conclusion: Percutaneous CT-guided cryoablation seems a safe and feasible treatment for complex thoracic lesions.

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