Nature Communications (Jun 2022)

Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid)

  • Morgan B. Giles,
  • Justin K. Y. Hong,
  • Yayuan Liu,
  • Jie Tang,
  • Tinghui Li,
  • Avital Beig,
  • Anna Schwendeman,
  • Steven P. Schwendeman

DOI
https://doi.org/10.1038/s41467-022-30813-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Encapsulation of bioactive peptides in slow-release particles is complex and relies on organic solvents. Here, the authors absorb peptides in a polymer phase from water, creating a simple low-cost encapsulation process in a class of polymer depot.