DIAGNOSE OF THYPOID FEVER WITH WIDAL TEST

Abstract

Thypoid fever is one of infection systemic disease cause by Salmonella enterica serotype typhi, thisbacterium is member of family Enterobacteriaciae. Everyone with thypoid fever bring thebacterium in blood stream and gastrointestinal sytem so that it can transmit the infection to othersdirectly through water or food that has been contaminated. Laboratory examination to establish adiagnosis of typhoid fever is with conventional methods, namely the culture of the bacterium andserological test Widal and non-conventional method, namely Polimerase Chain Reaction (PCR),Enzyme Immunoassay Dot (EID) and Enzyme-Linked Immunosorbent Assay (ELISA). The definitivediagnosis of typhoid fever is with isolation of Salmonella enterica serotype typhi from blood, urineor other body fluids. It is often not possible in developing countries because of inadequatebakteriologik facilities on many small hospitals, while typhoid fever is an endemic disease in thecountry. With this kind of situation, the diagnosis should be enforced by connecting thecorresponding clinical symptoms with typhoid fever and the presence of antibody titer is increasingsignificantly in the blood against antigens O or H antigens of Salmonella enterica serotype typhi(Widal test).

Keywords

• Thypoid fever, Widal test