Nutrients (Jun 2022)

Synergistic Effects of the Geriatric Nutritional Risk Index and the Modified Creatinine Index for Predicting Mortality in Patients on Hemodialysis

  • Takayuki Naito,
  • Toshiki Doi,
  • Kenichi Morii,
  • Koji Usui,
  • Michiko Arita,
  • Kazuomi Yamashita,
  • Kenichiro Shigemoto,
  • Yoshiko Nishizawa,
  • Sonoo Mizuiri,
  • Kensuke Sasaki,
  • Takao Masaki

DOI
https://doi.org/10.3390/nu14122398
Journal volume & issue
Vol. 14, no. 12
p. 2398

Abstract

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This study aimed to investigate whether a combined estimation of the geriatric nutritional risk index (GNRI) and the modified creatinine index (mCI) provides synergistic information for mortality in patients treated by chronic hemodialysis. We analyzed 499 patients on hemodialysis for five years. We set each cut-off value as the high (≥92) and low (p < 0.05) than G1 but not G3. Using the multivariable-adjusted model, only G4 was significantly associated with all-cause mortality compared with G1. Our study suggests that the synergistic effects of the GNRI and the mCI are helpful in predicting all-cause mortality. The combination of these indices may be superior to a single method to distinguish patients who are well or moderately ill from potentially severely ill.

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