Drug-induced sleep endoscopy (DISE) is a complementary method for the diagnosis of obstruction sites in patients with snoring and obstructive sleep apnea (OSA) and allows the optimization of treatment. We present the first case of a patient having a seizure during DISE, after sedation with midazolam and propofol. We recommend that DISE should be performed in a safe environment, under monitoring, and with anesthesia equipment that can be used to counteract potential complications caused by seizures.
