Clinical and Applied Thrombosis/Hemostasis (Apr 2021)

Clinical Outcomes of Pulmonary Embolism in Mexican Patients With COVID-19

  • Luis O. Bobadilla-Rosado MD,
  • Santiago Mier y Teran-Ellis MD,
  • Gabriel Lopez-Pena MD, ChM,
  • Javier E. Anaya-Ayala MD, MSc,
  • Carlos A. Hinojosa MD, MSc

DOI
https://doi.org/10.1177/10760296211008988
Journal volume & issue
Vol. 27

Abstract

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Coagulation abnormalities have been reported in COVID-19 patients, which may lead to an increased risk of Pulmonary Embolism (PE). We aimed to describe the clinical characteristics and outcomes of COVID-19 patients diagnosed with PE during their hospital stay. We analyzed patients with PE and COVID-19 in a tertiary center in Mexico City from April to October of 2020. A total of 26 (100%) patients were diagnosed with Pulmonary Embolism and COVID-19. We observed that 14 (54%) patients were receiving either prophylactic or full anticoagulation therapy, before PE diagnosis. We found a significant difference in mortality between the group with less than 7 days (83%) and the group with more than 7 days (15%) in Intensive Care Unit ( P = .004); as well as a mean of 8 days for the mortality group compared with 20 days of hospitalization in the survivor group ( P = .003). In conclusion, there is an urgent need to review antithrombotic therapy in these patients in order to improve clinical outcomes and decrease hospital overload.