Analysis of metabolic networks controlled by microRNAs in zebrafish

Abstract

MicroRNAs regulate gene expression at post-transcriptional level. The potential target of a miRNA can be computationally individuated, through a comparison of sequences. Here are presented the preliminary data obtained from a bioinformatic retrieval of the miRNAs involved in the regulation of the arginine metabolism in zebrafish, through the web resource MicroCosm Target (EBI). The potential "key miRNAs" individuated (miR-194b, miR-738 and miR-132*) in this pathway should be considered for an experimental validation.

Keywords

• arginine metabolism, miRNA, zebrafish