mBio
(Jun 2021)
The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons
Manasa Bharathwaj,
Chaille T. Webb,
Grishma Vadlamani,
Christopher J. Stubenrauch,
Tracy Palmer,
Trevor Lithgow
Affiliations
Manasa Bharathwaj
Infection & Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia
Chaille T. Webb
Infection & Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia
Grishma Vadlamani
Infection & Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia
Christopher J. Stubenrauch
ORCiD Infection & Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia
Tracy Palmer
Microbes in Health and Disease, Newcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
Trevor Lithgow
ORCiD Infection & Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria, Australia
DOI
https://doi.org/10.1128/mBio.01302-21
Journal volume & issue
Vol. 12,
no. 3
Abstract
Read online
Bacteria can readily acquire plasmids via lateral gene transfer (LGT). These plasmids can carry genes for virulence and antimicrobial resistance (AMR).
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