Changes of Trigeminal Ganglion Neurons Innervating the Temporomandibular Joint in Chronic Pain Rat Model

Wen Liu; Henghua Jiang; Jin Ke; Xin Liu; Yaping Feng; Jinsong Hou; Xing Long

doi:10.1155/2024/7015382

International Journal of Dentistry (Jan 2024)

Changes of Trigeminal Ganglion Neurons Innervating the Temporomandibular Joint in Chronic Pain Rat Model

Wen Liu,
Henghua Jiang,
Jin Ke,
Xin Liu,
Yaping Feng,
Jinsong Hou,
Xing Long

Affiliations

Wen Liu: Department of Oral and Maxillofacial Surgery
Henghua Jiang: State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration
Jin Ke: State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration
Xin Liu: State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration
Yaping Feng: State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration
Jinsong Hou: Department of Oral and Maxillofacial Surgery
Xing Long: State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration

DOI: https://doi.org/10.1155/2024/7015382
Journal volume & issue: Vol. 2024

Abstract

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Conclusion: This study suggests that sensitization of small- to medium-sized Dil+ TG neurons and CGRP- and IB4-positive Dil+ TG neurons might contribute to the development of TMJOA chronic pain in rats. This will provide valuable information for more efficient control of TMJOA chronic pain.

Published in International Journal of Dentistry

ISSN: 1687-8728 (Print); 1687-8736 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Dentistry
Website: https://onlinelibrary.wiley.com/journal/6164

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