Journal of Medical Case Reports (Mar 2010)

Mycosis fungoides bullosa: a case report and review of the literature

  • Bröcker Eva-B,
  • Kneitz Hermann,
  • Becker Jürgen C

DOI
https://doi.org/10.1186/1752-1947-4-78
Journal volume & issue
Vol. 4, no. 1
p. 78

Abstract

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Abstract Introduction Mycosis fungoides, the most common type of cutaneous T-cell lymphoma, can manifest in a variety of clinical and histological forms. Bulla formation is an uncommon finding in mycosis fungoides and only approximately 20 cases have been reported in the literature. Case presentation We present a case of rapidly progressive mycosis fungoides in a 68-year-old Caucasian man who initially presented with erythematous plaques characterised by blister formation. Conclusion Although mycosis fungoides bullosa is extremely rare, it has to be regarded as an important clinical subtype of cutaneous T-cell lymphoma. Mycosis fungoides bullosa represents a particularly aggressive form of mycosis fungoides and is associated with a poor prognosis. The rapid disease progression in our patient confirms bulla formation as an adverse prognostic sign in cutaneous T-cell lymphoma.