Response assessment in acute myeloid leukemia by flow cytometry supersedes cytomorphology at time of aplasia, amends cases without molecular residual disease marker and serves as an independent prognostic marker at time of aplasia and post-induction

• Thomas Köhnke,
• Veit Bücklein,
• Sandra Rechkemmer,
• Stephanie Schneider,
• Maja Rothenberg-Thurley,
• Klaus H. Metzeler,
• Maria-Cristina Sauerland,
• Wolfgang Hiddemann,
• Karsten Spiekermann,
• Marion Subklewe

Affiliations

Thomas Köhnke

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;Translational Cancer Immunology, Gene Center, LMU Munich, Munich

Veit Bücklein

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;Translational Cancer Immunology, Gene Center, LMU Munich, Munich

Sandra Rechkemmer

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich

Stephanie Schneider

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;Institute of Human Genetics, LMU Munich, Munich

Maja Rothenberg-Thurley

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;German Cancer Consortium (DKTK), Heidelberg;German Cancer Research Center (DKFZ), Heidelberg

Klaus H. Metzeler

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;German Cancer Consortium (DKTK), Heidelberg;German Cancer Research Center (DKFZ), Heidelberg

Maria-Cristina Sauerland

Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

Wolfgang Hiddemann

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;German Cancer Consortium (DKTK), Heidelberg;German Cancer Research Center (DKFZ), Heidelberg

Karsten Spiekermann

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;German Cancer Consortium (DKTK), Heidelberg;German Cancer Research Center (DKFZ), Heidelberg

Marion Subklewe

Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich;Translational Cancer Immunology, Gene Center, LMU Munich, Munich;German Cancer Consortium (DKTK), Heidelberg;German Cancer Research Center (DKFZ), Heidelberg