The higher prevalence of missense mutations in hemophilia B compared to hemophilia A could be important in determining a milder clinical phenotype in patients with severe hemophilia B
Daniela Melchiorre,
Silvia Linari,
Giancarlo Castaman
Affiliations
Daniela Melchiorre
Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Rheumatology Unit, Careggi University Hospital, Florence, Italy
Silvia Linari
Center for Bleeding Disorders, Careggi University Hospital, Florence, Italy
Giancarlo Castaman
Center for Bleeding Disorders, Careggi University Hospital, Florence, Italy