Romanian Journal of Laboratory Medicine (Apr 2021)

Reliability of Friedewald formula in patients with type 2 diabetes mellitus and its relation to lipid profile in diabetes regulation

  • Keti Didem Barlak,
  • Muhtaroglu Sabahattin

DOI
https://doi.org/10.2478/rrlm-2021-0007
Journal volume & issue
Vol. 29, no. 2
pp. 179 – 187

Abstract

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Introduction: Many laboratories utilize Friedewald formula (FF) to analyze LDL cholesterol levels of patients including diabetes mellitus (DM). Therefore, it is essential to consider the coherence of results acquired by FF and direct measurement. The number of studies that investigated the effect of lipid parameters, especially TG/HDL cholesterol ratio, on the difference between the two methods is limited. The study was designed to compare LDL cholesterol values obtained by using FF with direct measurement, and to evaluate the relationship between diabetes regulation and lipid profile.

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