Green Routes for Bio-Fabrication in Biomedical and Pharmaceutical Applications
Carla Serri,
Iriczalli Cruz-Maya,
Irene Bonadies,
Giovanna Rassu,
Paolo Giunchedi,
Elisabetta Gavini,
Vincenzo Guarino
Affiliations
Carla Serri
Department of Medicine, Surgery and Pharmacy, University of Sassari, Via Muroni 23/a, 07100 Sassari, Italy
Iriczalli Cruz-Maya
Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Mostra d’Oltremare Pad. 20, V.le J.F. Kennedy 54, 80125 Naples, Italy
Irene Bonadies
Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Mostra d’Oltremare Pad. 20, V.le J.F. Kennedy 54, 80125 Naples, Italy
Giovanna Rassu
Department of Medicine, Surgery and Pharmacy, University of Sassari, Via Muroni 23/a, 07100 Sassari, Italy
Paolo Giunchedi
Department of Medicine, Surgery and Pharmacy, University of Sassari, Via Muroni 23/a, 07100 Sassari, Italy
Elisabetta Gavini
Department of Medicine, Surgery and Pharmacy, University of Sassari, Via Muroni 23/a, 07100 Sassari, Italy
Vincenzo Guarino
Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Mostra d’Oltremare Pad. 20, V.le J.F. Kennedy 54, 80125 Naples, Italy
In the last decade, significant advances in nanotechnologies, rising from increasing knowledge and refining of technical practices in green chemistry and bioengineering, enabled the design of innovative devices suitable for different biomedical applications. In particular, novel bio-sustainable methodologies are developing to fabricate drug delivery systems able to sagely mix properties of materials (i.e., biocompatibility, biodegradability) and bioactive molecules (i.e., bioavailability, selectivity, chemical stability), as a function of the current demands for the health market. The present work aims to provide an overview of recent developments in the bio-fabrication methods for designing innovative green platforms, emphasizing the relevant impact on current and future biomedical and pharmaceutical applications.