Efficacy of application of alginates in treatment of a heartburn at pregnant women

Abstract

Aim of investigation. To estimate frequency, factors of development of heartburn at pregnant women, to determine approach of pharmaceutical treatment by alginates.Material and methods. At 110 pregnant women frequency and severity of heartburn were estimated by Likert scale, anthropometry and esophagogastroduodenoscopy at presence of heartburn were carried out.Results. General frequency of symptom of heartburn in studied group was 56,4%. The weekly heartburn was revealed at every other pregnant woman (49,1%). The greatest effect on its development had: presence of heartburn prior pregnancy, excessive body weight or obesity before and during pregnancy, presence of the relatives having heartburn, presence of heartburn during previous pregnancy, smoking before pregnancy. Frequency and severity of heartburn without pharmacological correction grew along with gestation term. On a background of Gaviscon forte treatment 10 ml/day in on-demand mode by the 4-th week of the study significant decrease of total frequency and severity of heartburn, complete relief of weekly, daily and night heartburn was observed.Conclusion. The heartburn is a frequent symptom at pregnancy, alginic acid drug can be successfully utilised for its treatment.

Keywords

• symptom of heartburn
• pregnancy
• alginates
• gaviscon-forte