Synthesis of New Active Sulfones in the 5-Nitroimidazole Series

Abstract

We describe here the preparation of new 5-nitroimidazoles which are known to have an efficacy against metronidazole-susceptible and -resistant Giarda, Trichomonas, and Entamoeba spp. The multi-step synthesis uses electron transfer methodology.

Keywords

• Nitroimidazoles
• sulfones
• electron transfer