Pulse oximetry and oxygen services for the care of children with pneumonia attending frontline health facilities in Lagos, Nigeria (INSPIRING-Lagos): study protocol for a mixed-methods evaluation
Hamish R Graham,
Adegoke G Falade,
Tim Colbourn,
Eric D McCollum,
Ayobami Adebayo Bakare,
Carina King,
Christine Cassar,
Timothy Colbourn,
Omotayo E Olojede,
Agnese Iuliano,
Adamu Isah,
Adams Osebi,
Tahlil Ahmed,
Rochelle Ann Burgess,
Samy Ahmar,
Paula Valentine,
Ibrahim Haruna,
Abdullahi Magama,
Ibrahim Seriki,
Temitayo Folorunso Olowookere,
Matt MacCalla,
Obioma Uchendu,
Julius Salako,
Funmilayo Shittu,
Damola Bakare,
Ayobami Adebayo A Bakare,
Omotayo Olojede
Affiliations
Hamish R Graham
1 Centre for International Child Health, MCRI, University of Melbourne, The Royal Children’s Hospital Melbourne, Parkville, Victoria, Australia
Adegoke G Falade
Department of Paediatrics, University College Hospital, Ibadan, Nigeria
Tim Colbourn
Institute for Global Health, University College London, London, UK
Eric D McCollum
Global Program in Pediatric Respiratory Sciences, Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Ayobami Adebayo Bakare
Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden
Carina King
Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden
Christine Cassar
8 Save the Children Fund, London, UK
Timothy Colbourn
6 Institute for Global Health, University College London, London, UK
Omotayo E Olojede
Department of Paediatrics, University College Hospital, Ibadan, Nigeria
Agnese Iuliano
6 Institute for Global Health, University College London, London, UK
Adamu Isah
7 Save the Children International, Abuja, FCT, Nigeria
Adams Osebi
7 Save the Children International, Abuja, FCT, Nigeria
Tahlil Ahmed
8 Save the Children Fund, London, UK
Rochelle Ann Burgess
6 Institute for Global Health, University College London, London, UK
Samy Ahmar
8 Save the Children Fund, London, UK
Paula Valentine
8 Save the Children Fund, London, UK
Ibrahim Haruna
Abdullahi Magama
Ibrahim Seriki
7 Save the Children International, Abuja, FCT, Nigeria
Temitayo Folorunso Olowookere
9 GlaxoSmithKline (GSK), Lagos, Nigeria
Matt MacCalla
10 GlaxoSmithKline (GSK), Brentford, UK
Obioma Uchendu
Community Medicine Department, University of Ibadan College of Medicine, Ibadan, Nigeria
Julius Salako
Department of Paediatrics, University College Hospital, Ibadan, Nigeria
Funmilayo Shittu
Damola Bakare
Department of Paediatrics, University College Hospital, Ibadan, Nigeria
Ayobami Adebayo A Bakare
Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden
Introduction The aim of this evaluation is to understand whether introducing stabilisation rooms equipped with pulse oximetry and oxygen systems to frontline health facilities in Ikorodu, Lagos State, alongside healthcare worker (HCW) training improves the quality of care for children with pneumonia aged 0–59 months. We will explore to what extent, how, for whom and in what contexts the intervention works.Methods and analysis Quasi-experimental time-series impact evaluation with embedded mixed-methods process and economic evaluation. Setting: seven government primary care facilities, seven private health facilities, two government secondary care facilities. Target population: children aged 0–59 months with clinically diagnosed pneumonia and/or suspected or confirmed COVID-19. Intervention: ‘stabilisation rooms’ within participating primary care facilities in Ikorodu local government area, designed to allow for short-term oxygen delivery for children with hypoxaemia prior to transfer to hospital, alongside HCW training on integrated management of childhood illness, pulse oximetry and oxygen therapy, immunisation and nutrition. Secondary facilities will also receive training and equipment for oxygen and pulse oximetry to ensure minimum standard of care is available for referred children. Primary outcome: correct management of hypoxaemic pneumonia including administration of oxygen therapy, referral and presentation to hospital. Secondary outcome: 14-day pneumonia case fatality rate. Evaluation period: August 2020 to September 2022.Ethics and dissemination Ethical approval from University of Ibadan, Lagos State and University College London. Ongoing engagement with government and other key stakeholders during the project. Local dissemination events will be held with the State Ministry of Health at the end of the project (December 2022). We will publish the main impact results, process evaluation and economic evaluation results as open-access academic publications in international journals.Trial registration number ACTRN12621001071819; Registered on the Australian and New Zealand Clinical Trials Registry.