Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis

Affiliations

Ling Yu: The Second Clinical College, Guangzhou University of Chinese Medicine
Yubin Liang: The Second Clinical College, Guangzhou University of Chinese Medicine
Minzhou Zhang: The Second Clinical College, Guangzhou University of Chinese Medicine
Phillip C. Yang: Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine
Aleksander Hinek: Translational Medicine, Hospital for Sick Children
Shuai Mao: The Second Clinical College, Guangzhou University of Chinese Medicine

Abstract

The circular RNA circCEBPZOS, present in extracellular vesicles, promotes revascularization and alleviates postinfarct cardiac remodeling.