Biomarkers in saliva as diagnostic tool in early diagnosis of oral submucous fibrosis

Abstract

The potentially malignant lesions of oral cavity pose a sensitive challenge to the public health status. The risk is considerably high of malignant transformation of oral submucous fibrosis (OSMF) into oral cancer. The more rapidly they get diagnosed early, the better it is for public oral health. The need of the hour is to put into general practice the minimally invasive and noninvasive procedures of diagnostics for these lesions. Salivary biomarkers are recently advanced diagnostic tools fit for the requirement. With more researches and developments in technology, they are becoming a fast and with ease both patient and clinician-friendly choice and also medically appropriate. High expectations are that salivary biomarkers become sole noninvasive and exact method of diagnosing premalignant disorders such as OSMF.

Keywords

• biomarkers
• diagnosis
• malignancies
• oral health
• oral submucous fibrosis