Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans

Kyung Suk Lee; Shachar Iwanir; Ronen B. Kopito; Monika Scholz; John A. Calarco; David Biron; Erel Levine

doi:10.1038/ncomms14221

Nature Communications (Feb 2017)

Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans

Kyung Suk Lee,
Shachar Iwanir,
Ronen B. Kopito,
Monika Scholz,
John A. Calarco,
David Biron,
Erel Levine

Affiliations

Kyung Suk Lee: Department of Physics, Harvard University
Shachar Iwanir: Department of Physics and the James Franck Institute, The University of Chicago
Ronen B. Kopito: Department of Physics, Harvard University
Monika Scholz: Department of Physics and the James Franck Institute, The University of Chicago
John A. Calarco: FAS Center for Systems Biology, Harvard University
David Biron: Department of Physics and the James Franck Institute, The University of Chicago
Erel Levine: Department of Physics, Harvard University

DOI: https://doi.org/10.1038/ncomms14221
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 11

Abstract

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Regulating food intake is an important physiological mechanism. Here, the authors use a custom microfluidic device to investigate feeding dynamics inC. elegans, and identify roles of serotonergic neurons in regulating bursts of feeding in response to food availability.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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