Frontiers in Chemistry (May 2023)

Raman and fourier transform infrared spectroscopy techniques for detection of coronavirus (COVID-19): a mini review

  • Qiuqi Zhang,
  • Lei Zhao,
  • Guoliang Qi,
  • Xiaoru Zhang,
  • Cheng Tian

DOI
https://doi.org/10.3389/fchem.2023.1193030
Journal volume & issue
Vol. 11

Abstract

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Coronavirus pandemic has been a huge jeopardy to human health in various systems since it outbroke, early detection and prevention of further escalation has become a priority. The current popular approach is to collect samples using the nasopharyngeal swab method and then test for RNA using the real-time polymerase chain reaction, which suffers from false-positive results and a longer diagnostic time scale. Alternatively, various optical techniques, namely, optical sensing, spectroscopy, and imaging shows a great promise in virus detection. In this mini review, we briefly summarize the development progress of vibrational spectroscopy techniques and its applications in the detection of SARS-CoV family. Vibrational spectroscopy techniques such as Raman spectroscopy and infrared spectroscopy received increasing appreciation in bio-analysis for their speediness, accuracy and cost-effectiveness in detection of SARS-CoV. Further, an account of emerging photonics technologies of SARS-CoV-2 detection and future possibilities is also explained. The progress in the field of vibrational spectroscopy techniques for virus detection unambiguously show a great promise in the development of rapid photonics-based devices for COVID-19 detection.

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