Pharmacokinetics and pharmacodynamics of a β-adrenoblocker bisoprolol: from mechanisms of action to clinical features

Abstract

The authors discuss the action mechanisms of β-adrenoblockers (β-AB), as well as pharmacokinetics, pharmacodynamics, and drug interaction of a highly selective β-AB bisoprolol. The paper presents the data on bisoprolol effectiveness and safety in arterial hypertension, coronary heart disease, chronic heart failure, and their combination with other diseases.

Keywords

• β-адреноблокатор
• бисопролол
• артериальная гипертония
• ишемическая болезнь сердца
• хроническая сердечная недостаточность