Frontiers in Immunology (Oct 2024)

Lung enteric-type adenocarcinoma with gastric metastasis: a rare case report and literature review

  • Xiaoning Li,
  • Kewei Ma,
  • Xiaobo Ma,
  • Xiangye Zhao,
  • Mengge Fan,
  • Yinghui Xu

DOI
https://doi.org/10.3389/fimmu.2024.1486214
Journal volume & issue
Vol. 15

Abstract

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Lung enteric-type adenocarcinoma (ETAC) is a rare subtype of non-small cell lung cancer (NSCLC), comprising approximately 0.6% of all primary lung adenocarcinomas. It is characterized by a tendency for early metastasis and a prognosis comparable to that of common lung adenocarcinoma. This case report described a patient with lung-ETAC who developed gastric metastasis. The patient underwent treatment with chemotherapy and a PD-1 inhibitor, resulting in disease remission with a progression-free survival (PFS) of 8 months. The follow-up time was 13 months. This case report was aimed to enhance understanding of the biological behavior of this rare tumor and provide insights into potential future treatment strategies.

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