Dyslipidemia among allergic rhinitis patients: Frequency and risk factors

Dina S. Sheha; Lobna A. El-Korashi; Amany M. AbdAllah; Marwa M. El-Begermy; Amira R. Elmahdi

World Allergy Organization Journal (Mar 2021)

Dyslipidemia among allergic rhinitis patients: Frequency and risk factors

Dina S. Sheha,
Lobna A. El-Korashi,
Amany M. AbdAllah,
Marwa M. El-Begermy,
Amira R. Elmahdi

Affiliations

Dina S. Sheha: Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt; Corresponding author. Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, El-Khalyfa El-Mamoun Street; El-Abaseya, Cairo, 11566 Egypt
Lobna A. El-Korashi: Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt; Corresponding author. Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig University, 12 Abdaziz Ali Street, Zagazig, Al Sharqia governorate, 44519 Egypt
Amany M. AbdAllah: Department of Family Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Marwa M. El-Begermy: Department of Otorhinolaryngology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Amira R. Elmahdi: Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Journal volume & issue: Vol. 14, no. 3
p. 100523

Abstract

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Background: Although cumulative data strongly suggest an association between dyslipidemia and allergic disorders, especially asthma, evidence regarding allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated risk factors of dyslipidemia among patients with AR. Methods: The current study is a cross-sectional study that recruited 150 AR patients by systematic randomization. Blood samples for serum lipid profile, total immunoglobulin E (IgE) and serum interleukin-17A (IL-17A) were withdrawn from all patients. Results: Dyslipidemia was prevalent in 84 AR patients (56%). Higher levels of total IgE, IL17-A, and sensitization to hay dust and mixed mites significantly increased the risk of dyslipidemia among AR patients by 1.004, 1.062, 4.057 and 3.652 respectively (P < 0.05). Conclusion: High serum total IgE level, high serum IL-17A level, and sensitization to hay dust and mixed mites are independent risk factors for dyslipidemia among AR patients.

Published in World Allergy Organization Journal

ISSN: 1939-4551 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: https://www.sciencedirect.com/journal/world-allergy-organization-journal

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