Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI

Shogo Doi; Yasuyoshi Kuroiwa, PhD; Kazunori Kusumoto, MD; Atsushi Yamashita, MD, PhD; Eiji Furukoji, MD, PhD; Hiroshi Tai, MD; Yasushi Kihara, MD; Toshinori Hirai, MD, PhD; Yujiro Asada, MD, PhD; Takuroh Imamura, MD, PhD

Radiology Case Reports (Sep 2019)

Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI

Shogo Doi,
Yasuyoshi Kuroiwa, PhD,
Kazunori Kusumoto, MD,
Atsushi Yamashita, MD, PhD,
Eiji Furukoji, MD, PhD,
Hiroshi Tai, MD,
Yasushi Kihara, MD,
Toshinori Hirai, MD, PhD,
Yujiro Asada, MD, PhD,
Takuroh Imamura, MD, PhD

Affiliations

Shogo Doi: Department of Radiological Technology, Koga General Hospital, Miyazaki, Japan
Yasuyoshi Kuroiwa, PhD: Department of Radiological Technology, Koga General Hospital, Miyazaki, Japan; Department of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan
Kazunori Kusumoto, MD: Department of Internal Medicine, Koga General Hospital, Miyazaki, Japan
Atsushi Yamashita, MD, PhD: Department of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan; Corresponding author.
Eiji Furukoji, MD, PhD: Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
Hiroshi Tai, MD: Department of Internal Medicine, Koga General Hospital, Miyazaki, Japan
Yasushi Kihara, MD: Department of Radiology, Koga General Hospital, Miyazaki, Japan
Toshinori Hirai, MD, PhD: Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
Yujiro Asada, MD, PhD: Department of Pathology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan
Takuroh Imamura, MD, PhD: Department of Internal Medicine, Koga General Hospital, Miyazaki, Japan

Journal volume & issue: Vol. 14, no. 9
pp. 1132 – 1135

Abstract

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Immunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult to assess aortic inflammatory activity of IgG4-related disease. We described a case of IgG4-related pancreatitis and aortitis, which was visualized with magnetic resonance merged image of diffusion weighted and T1 weighted images. The aortic signal intensity or apparent diffusion coefficient value reduced or increased after oral prednisone administration, respectively. Magnetic resonance diffusion weighted image and apparent diffusion coefficient may be a useful imaging tool for assessment of vascular inflammation in IgG4-related aortitis. Keywords: Immunoglobulin (IgG) 4-related disease, Aortitis, Magnetic resonance imaging, Diffusion weighted imaging

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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