Nature Communications (Aug 2020)

Sex differences in oncogenic mutational processes

  • Constance H. Li,
  • Stephenie D. Prokopec,
  • Ren X. Sun,
  • Fouad Yousif,
  • Nathaniel Schmitz,
  • PCAWG Tumour Subtypes and Clinical Translation,
  • Paul C. Boutros,
  • PCAWG Consortium

DOI
https://doi.org/10.1038/s41467-020-17359-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 24

Abstract

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There’s an emerging body of evidence to show how biological sex impacts cancer incidence, treatment and underlying biology. Here, using a large pan-cancer dataset, the authors further highlight how sex differences shape the cancer genome.