Diagnosis and prognosis of myocardial infarction on a plasmonic chip

Wei Xu; Lin Wang; Ru Zhang; Xuming Sun; Lin Huang; Haiyang Su; Xunbin Wei; Chia-Chun Chen; Jiatao Lou; Hongjie Dai; Kun Qian

doi:10.1038/s41467-020-15487-3

Nature Communications (Apr 2020)

Diagnosis and prognosis of myocardial infarction on a plasmonic chip

Wei Xu,
Lin Wang,
Ru Zhang,
Xuming Sun,
Lin Huang,
Haiyang Su,
Xunbin Wei,
Chia-Chun Chen,
Jiatao Lou,
Hongjie Dai,
Kun Qian

Affiliations

Wei Xu: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Lin Wang: Department of Laboratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University
Ru Zhang: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Xuming Sun: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Lin Huang: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Haiyang Su: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Xunbin Wei: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University
Chia-Chun Chen: Department of Chemistry, National Taiwan Normal University
Jiatao Lou: Department of Laboratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University
Hongjie Dai: Department of Chemistry, Stanford University
Kun Qian: School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University

DOI: https://doi.org/10.1038/s41467-020-15487-3
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

Read online

The gold standard for diagnosis and monitoring of myocardial infarction is a chemiluminescence assay based on the detection of cardian troponin I (cTnI). Here, the authors develop a plasmonic gold nano-island chip assay for ultrasensitive detection of cTnI in as little as 10 μL of serum.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal