Two new inorganic-organic hybrid compounds: photocatalytic, luminescent property and treatment activity on polycystic ovary syndrome

Abstract

Two new mixed-ligand-based compounds, namely [Co(1,3-pde)(4-bpmh)]n (1) and [Zn3(3,3’-bpdc)3(4-bpmh)1.5]n (2) (1,3-H2pde = 1,3-phenylenediacetic acid, 3,3’-H2bpdc = biphenyl-3,3'-dicarboxylic acid, 4-bpmh = N,N-bis-pyridin-4-ylmethylene-hydrazine) have been prepared under hydrothermal conditions. The obtained compounds were determined by singe crystalX-ray diffraction analyses, elemental analyses, powder X-ray diffraction analyses and thermogravimetric analyses. Moreover, the photocatalytic activity of 1 and luminescent property of 2 have also been investigated. This presented research estimate their treatment activity of the polycystic ovary syndrome, also the mechanism was measured as well. Firstly, a relative expression of the estrogen receptor on the ovarian epithelial cells was determined with real time RT-PCR. In addition, the amount of progesterone of the plasma was measured with ELISA detection kit after indicated treatment.

Keywords

• hydrothermal synthesis
• topology
• luminescence
• photocatalysis
• polycystic ovary syndrome