Journal of Medicinal Plants (Nov 2011)
Study of Intravenous Injection of Hydroalcoholic Extract of Crataegus oxycantha on Lung and Aorta Arteries Echocardiography in Healthy Horses
Abstract
Background: Reduced productivity due to cardiovascular disease in horses known as the third. Today, a number of drugs with different properties for the treatment of cardiovascular disease in horses which used when considering the need for newer drugs and their side effects are felt. Numerous studies on the effects of cardiovascular drugs and their effects have been carried out to examine the effects of echocardiography is used frequently. One of the most important medicinal plants is Crataegus oxycantha that has various properties such as antihypertensive, anti-arrhythmic and vasodilatory effects for it and other Crataegus species are considered. Methods: In this study of 14 healthy head of race TARVBORD with age range from 9 to 15 years and weighing 340 kg up to 420 kg were used. Horses were divided in to two equal groups and treated. The amount of extract-treated group and control group, normal saline with the same volume of 2 mg/kg for 6 weeks, to bead ministered intravenously. The two-dimensional echocardiography to measure changes in lung arteries and the aorta was used. Results: The size of PA, PAS and AO after injection treatment group than the control group showed significant increases in both groups were followed. Conclusion: According to the results of research Crataegus oxycantha in horses has properties of vascular dilation and reduced their blood pressure, which can be in reducing cardiac after load, decreased blood pressure and swelling of lung tissue toxin used sheets.