Медицинский совет (Jan 2018)

EXPERIENCE IN USING SODIUM AMINODYHYDROPHTALAZINDIONE AS PART OF COMBINATION THERAPY OF DISPLATIC CHANGES OF THE UTERINE CERVIX EPITHELIUM ASSOCIATED WITH ACUTE SPECIFIC INFLAMMATION

  • Yu. E. Dobrokhotova,
  • M. G. Venediktova,
  • A. N. Sarantsev,
  • K. V. Morozova,
  • A. E. Zykov,
  • A. Sh. Khasan,
  • N. P. Panova,
  • Yu. A. Savina,
  • V. A. Suvorova

DOI
https://doi.org/10.21518/2079-701X-2017-19-188-193
Journal volume & issue
Vol. 0, no. 20
pp. 188 – 193

Abstract

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One of the most significant problems of modern health care is the increasing incidence of malignant neoplasms of different localization, in particular cervical cancer. Malignant tumor of this localization develops on the basis of a cascade of precancerous changes in the cervix epithelium. Cervical dysplasia is a multifactorial disease, but the inflammation factor, especially associated with the presence of a specific pathogenic agent plays a major role in the unrelenting growth of cancer cells. When planning combination therapy in the settings of the inflammatory process, not only etiotropic therapy aimed at eliminating the pathogen, but also the correction of the immune status is of great importance, which makes it possible to achieve a stable therapeutic effect, including accelerating the regress of dysplastic changes in the cervical epithelium. Our examination and treatment of 47 patients with cervical dysplasia associated with colpitis of specific etiology (T. vaginalis, C. trachromatis) proved the advantage of combination therapy with Galavit as compared with the standard course of antibacterial and anti-inflammatory therapy.

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